ISSCR launches digital meeting series on nuclear architecture in stem cells
Skokie, IL – The International Society for Stem Cell Research (ISSCR) is hosting a four-part digital meeting series, Chromatin, Epigenetics, and Nuclear Architecture in Stem Cells, featuring a global line-up of speakers discussing chromatin, the fundamental unit of life. Comprised of DNA wrapped around a core of histone proteins and additional structural proteins, chromatin and its structure fundamentally regulates essentially all cellular processes via changes in its structure and its impact on gene regulation. With advances in labeling and imaging, genome editing and sequencing technologies, insight into these processes is accelerating and providing important insights into the complex biology of stem cell function.
Held in parallel with a special issue of Stem Cell Reports on nuclear architecture, the meeting series features leading scientists who will explore how and why such changes in chromatin structure are particularly pertinent in stem cells, which maintain potency on the one hand, but undergo massive